The building of the church began in 1619. The façade was built in 1834 and is the work of Ferdinando Caronesi, whose plans were inspired by the designs of Filippo Juvarra for the nearby church of Santa Cristina. Inside the church on each side of the main altar are paintings of San Carlo attributed to Giovanni Paolo Recchi. There is a statue of the Madonna della Pace by Tommaso Carlone in the small chapel which was built by Carlo Busso and Giovanni Battista Casella.